3M™ Harvest RC

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Single-stage, single-use chromatographic clarification solution.

Replaces primary, secondary, and guard membrane clarification stages.

Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid.

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Details

Highlights
  • Single-stage, single-use chromatographic clarification solution
  • Replaces primary, secondary, and guard membrane clarification stages
  • Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid
  • High mAb product recovery (90-95%)
  • Predictably scales from laboratory to manufacturing
  • Turbidity of 3M™ Harvest RC clarified cell culture fluid <15 NTU

3M™ Harvest RC is the next generation in harvest and clarification technology for high cell density cultures.

This solution is designed as an efficient option to increase monoclonal antibody (mAb) yields while simplifying the upstream process by replacing the centrifuge and/or depth filtration unit operations.

Suggested applications
  • Clarification for CHO harvest cell culture fluid
  • Single-stage chromatographic clarification

Specifications

Applications

Biopharmaceutical Manufacturing, Bioprocessing, Cell Culture Clarification, DNA Reduction, Fiber Chromatography, mAb Production, Single Stage Clarification, Turbidity Reduction

Autoclavable

Yes

Brands

3M™

Capsule Material

Polycarbonate

Effective Filtration Area (metric)

2.3 cm²

Factory Integrity Tested

Capsule Leak Test

Fill Volume

15 mL

Filter Material

Functional Non-woven

Filter Technology

Anion exchange chromatography

Filter Type

Single Use

Flux

0

Gamma Compatible

No

Gamma Sterilized

No

Industries

Life Sciences

Maximum Capacity

0

Maximum Operating Temperature (Celsius)

40 ℃

Membrane Type

PES

Micron Rating

0.2 μm

Product Series

Harvest RC

Shelf Life

2 Year

Storage Temperature (Celsius)

0 °C - 30 °C

Temperature Range (Celsius)

0 °C - 40 °C

Units per Case

4.0, 12.0

Overall Diameter (Metric)

2.9 cm

Overall Height (Metric)

6.1 cm, 8.9 cm

Overall Length (Metric)

12.7 cm

Overall Width (Metric)

8.6 cm

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